purified vaccine

Objective To prepare purified tick-borne encephalitis vaccine.

目的制备森林脑炎纯化疫苗.

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Screening of stabilizer of freeze-dried rabies purified vaccine for human use

冻干人用狂犬病纯化疫苗稳定剂的筛选

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The results of the quality analysis of the two different purified virus-containing fluids show that two different purified virus-containing fluids qualities all meet the specification of WHO and the two purified methods may all be used in preparation influenza vaccine.

对两种不同纯化方法得到的病毒原液进行质量分析，结果表明：用两种方法纯化后的病毒液质量都达到WHO规定的要求。两者均可作为流感疫苗（Influenza Vaccine）的纯化方法。

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Aim To study the immunogenicity and safety of purified Vero cell rabies vaccine for human use.

目的研究人用狂犬病纯化疫苗的安全性和保护性.

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Methods 240 cases bitten by dogs were chosen from outpatient and divided into two Experimental groups treatment with purified freezing-dried vero cell rabies vaccine and control group treated with purified rabies vaccine prepared with shrewmouse kidney cell according to the conventional procedures.

方法选择犬致伤者240例，随机分为试验组和对照组。实验组接种冻干Vero细胞狂犬病纯化疫苗，对照组接种地鼠肾狂犬病纯化疫苗。

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Conclusion The positive conversion rate of antibody in experimental group after immunized with purified vero cell rabies vaccine for human use is high and superior to the purified shrewmouse kidney cell rabies vaccine, and suitable for popularization.

结论冻干Vero细胞纯化疫苗抗体阳转率高、副反应发生率低，临床应用优于地鼠肾纯化疫苗，适宜推广使用。

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OBJECTIVETo investigate the efficacy of immunity of purified rabies vaccine for human and its adverse reaction.

目的了解人用精制狂犬病疫苗的免疫效果和人体副反应情况.

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In order to develop a mixed vaccine which consists of hCG-β-CTP-37 segment and the screened epitopes of oLH_ β, the preparation of highly purified oLH is an essential prerequisite.

为筛选oLHβ的抗原决定簇（epitopes），开发由hCGβ-CTP37和oLHβ最佳片段组成的复合疫苗，制备高纯度的oLH是必要前提。

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Study on Purified Japanese Encephalitis Virus Cell Culture Vaccine

提纯乙型脑炎细胞培养疫苗的研究

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The ED50 of 2 batches of vaccine prepared with the purified protein were 0.35 and 0.48 μ g/ ml respectively, while that of reference vaccine was 0.52 μ g/ ml.

两批纯化蛋白制备的疫苗ED50分别为0.35和0.48μg/ml，参比苗为0.52μg/ml。

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Conclusion Compared with those induced by original vaccine, the adverse reaction induced by the purified vaccine was mild, and the neutralizing antibody positive conversion rate was high. Purified tick-borne encephalitis vaccine might be an ideal substitute of original inactivated vaccine.

结论森林脑炎纯化疫苗较原制同类疫苗反应轻微，而中和抗体阳转率明显高于原制疫苗，是现用原制灭活疫苗理想的替代产品。

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